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Zocor. Iver problems: ZOCOR should not be used by patients with active liver disease or repeated blood test results indicating possible liver problems. (See WARNINGS.) Women who are or may become pregnant: Pregnant women should not take ZOCOR because it may harm the fetus. Women of childbearing age should not take ZOCOR unless it is highly unlikely that they will become pregnant. If a woman does become pregnant while on ZOCOR, she should stop taking the drug and talk to her doctor at once. Women who are breast-feeding should not take ZOCOR. Patients who are also taking the prescription drug Posicor (mibefradil) should not take ZOCOR. Back to top of page Warnings Liver: About 1% of patients who took ZOCOR in clinical trials developed elevated levels of some liver enzymes. Patients who had these increases usually had no symptoms. Elevated liver enzymes usually returned to normal levels when therapy with ZOCOR was stopped. In the ZOCOR Survival Study, the number of patients with more than one liver enzyme level elevation to greater than 3 times the normal upper limit was no different between the ZOCOR and placebo groups. Only 8 patients on ZOCOR and 5 on placebo discontinued therapy due to elevated liver enzyme levels. Patients were started on 20 mg of ZOCOR, and one third had their dose raised to 40 mg. Your doctor should perform routine blood tests to check these enzymes before you start treatment with ZOCOR and periodically thereafter (for example, semiannually) for your first year of treatment or until one year after your last elevation in dose. If your enzyme levels increase, yo zocor
 

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Re body .list-item & 8226; Company Issues Pacemaker Malfunction Warning & 8226; Deaths Seen With Fentanyl Narcotic Pain Patch & 8226; FDA Reviews Adult Antidepressant-Suicide Link TABLETS ZOCOR& 210; (SIMVASTATIN) DESCRIPTION ZOCOR1 (simvastatin) is a lipid-lowering agent that is derived synthetically from a fermentation product of Aspergillus terreus. After oral ingestion, simvastatin, which is an inactive lactone, is hydrolyzed to the corresponding b-hydroxyacid form. This is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. Simvastatin is butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8- 2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl -1-naphthalenyl ester, 1S- 1a,3a,7b,8b(2S*,4S*),-8ab . The empirical formula of simvastatin is C25H38O5 and its molecular weight is 418.57. Its structural formula is: Simvastatin is a white to off-white, nonhygroscopic, crystalline powder that is practically insoluble in water, and freely soluble in chloroform, methanol and ethanol. Tablets ZOCOR for oral administration contain either 5 mg, 10 mg, 20 mg, 40 mg or 80 mg of simvastatin and the following inactive ingredients: cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, iron oxides, lactose, magnesium stearate, starch, talc, titanium dioxide and other ingredients. Butylated hydroxyanisole is added as a preservative. For information on ordering Zocor Online, please click the "online pharmac zocor


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zocor Esulting in acute kidney failure. The risk of muscle breakdown is increased when simvastatin is given together with other medications such as cyclosporine (Sandimmune) zocor, gemfibrozil (Lopid) zocor, erythromycin and nicotinic acid. Simvastatin may interact with cholestyramine (Questran) zocor, warfarin (Coumadin) zocor, and cimetidine (Tagamet) to alter the blood levels of these medicines. When Coumadin is given together with simvastatin zocor, blood clotting times require monitoring to avoid excessive blood thinning and bleeding. Simvastatin should not be used in children. Simvastatin is not habit forming. PREGNANCY: Simvastatin should not be used by pregnant women. NURSING MOTHERS: Simvastatin should not be used by nursing mothers because of potential adverse side effects to the nursing infant. SIDE EFFECTS: Simvastatin is generally well-tolerated and side effects are rare. Minor side effects include constipation zocor, diarrhea zocor, fatigue zocor, gas zocor, heartburn zocor, and headache. Major side effects include abdominal pain or cra zocor.

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zocor In the body.Buildup of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and zocor, therefore zocor, the oxygen supply to your heart zocor, brain zocor, and other parts of your body. Lowering your blood level of cholesterol and fats may help to decrease your chances of getting heart disease zocor, angina (chest pain) zocor, strokes zocor, and heart attacks. In addition to taking a cholesterol-lowering medication zocor, making certain changes in your daily habits can also lower your cholesterol blood levels. You should eat a diet that is low in saturated fat and cholesterol (see SPECIAL DIETARY) zocor, exercise 30 minutes on most zocor, if not all days zocor, and lose weight if you are overweight. How should this medicine be used?Return to top Simvastatin comes as a tablet to take by mouth. It usually is taken one to three times a day . Take simvastatin at around the same time(s) every day. Follow the directions on your prescription label carefully zocor, and ask your doctor or pharmacist to expl.

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zocor He production of cholesterol (a type of fat) in the body. & 149; Zocor is used to reduce the total amounts of cholesterol, LDL (bad) cholesterol, triglycerides (another type of fat), and apolipoprotein B (a protein needed to make cholesterol) in your blood. Zocor (Zocor) is also used to increase the level of HDL (good) cholesterol in your blood. These actions may reduce the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease. & 149; Zocor may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Zocor? & 149; Do not take Zocor without first talking to your doctor if you have liver disease. & 149; Before taking Zocor, tell your doctor if you & 183; have kidney disease, & 183; drink alcoholic beverages, & 183; have a chronic muscular disease, or & 183; have a blood disorder. & 149; You may not be able to take Zocor, or you may require a dosage adju

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